Essential Supplements to Boost Your Health While on GLP-1 Medication

Kelsey Butler, MS, RDN
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5 minutes
Woman scooping protein powder

GLP-1 medications are highly effective for supporting weight loss and improving metabolic health. As a registered dietitian nutritionist, I’ve seen firsthand how powerful these treatments can be. They work by reducing appetite, regulating blood sugar, and promoting sustainable weight loss.

However, as appetite decreases and weight loss progresses, it’s not uncommon to see impacts on overall nutrient intake—especially if food volume drops significantly. Over time, this can lead to nutrient gaps that may affect energy levels, digestion, and muscle preservation.

If you’re on a GLP-1 treatment plan, it’s crucial to be proactive about your nutritional support. To help optimize your health and address potential deficiencies, here are the top supplements I recommend considering as part of your routine while taking a GLP-1:

1. Protein

Maintaining adequate protein intake is essential—especially when your goal is to lose fat, not muscle. Because GLP-1s often reduce appetite, it can be challenging to meet your daily protein needs through food alone. While many foods can provide sufficient protein, you may need additional support to maintain muscle health. Consider adding a protein supplement, such as whey or a plant-based protein powder, to help close the gap.

2. Fiber

GLP-1 medications may lead to changes in bowel movements, including constipation. A fiber supplement can help promote regularity and support digestive health. Be sure to increase fiber gradually and drink plenty of water—insufficient hydration can actually worsen constipation, the very issue fiber aims to address.

3. Multivitamins

GLP-1 medications can sometimes impact nutrient absorption, making it essential to cover potential gaps in your diet. A high-quality multivitamin can help ensure you receive the essential vitamins and minerals that support overall health. Choose a multivitamin that provides a broad spectrum of nutrients, including vitamins A, C, D, E, and B-complex, as well as key minerals like zinc and selenium.

4. B12/MIC

B12/MIC supplements may offer several health benefits, including boosting metabolism, increasing energy levels, improving sleep quality, and addressing Vitamin B12 deficiencies, which can be a side effect of GLP-1 medications. Additionally, B12/MIC may help reduce appetite and food cravings. Alan Meds offers a B12/MIC injectable to maximize weight reduction and boost energy.

5. Omega-3 Fatty Acids

Omega-3 fatty acids, found in fish oil or flaxseed oil supplements, offer numerous health benefits, including anti-inflammatory effects and support for cardiovascular health. While GLP-1 medications assist with weight management, they don’t address all aspects of heart health. Omega-3 supplements can help fill this gap and promote overall well-being.

Alan Health GLP-1 Nutrient Support Kit

To simplify your supplement routine, the Alan Health GLP-1 Nutrient Support Kit includes three of the most important nutrients for people on GLP-1s: protein, fiber, and multivitamins. This curated kit is designed to support muscle maintenance, digestive balance, and foundational health while you’re on your medication.

You can add this kit directly through your Alan Health portal or contact our Customer Care team at help@alanmeds.com for assistance.

Final Thoughts

As an RDN, my goal is to help you navigate weight loss in a way that prioritizes your overall health. GLP-1 medications are a powerful tool—but nutritional support plays a critical role in how you feel and function along the way.

By thoughtfully incorporating supplements like protein, fiber, multivitamins, B12, and omega-3s, you can help fill nutrient gaps, maintain muscle mass, and support digestion, energy, and overall well-being. When used alongside a balanced diet and clinical guidance, these tools can help you feel your best and get the most from your GLP-1 treatment plan.

Personalized Compounded Semaglutide
Effective weight management
Curb appetite
Stabilize blood sugar levels
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B12 / MIC
Boosts energy and metabolism
Supports fat burn and lean muscle
Breaks through weight loss plateaus
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B12 Injection
Helps reduce fatigue and support steady energy levels
Aids in maintaining focus, memory, and overall brain health
Supports red blood cell production and oxygen delivery
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Lipo C Complex
Burns fat more efficiently
Boosts energy naturally
Supports liver detox
Enhances metabolism
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Compounded Liraglutide
Highly effective weight support
Curbs appetite and sugar levels
Once-daily subcutaneous injection
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Personalized Compounded Tirzepatide
Prevent weight regain
Personalized dosing plan
Ongoing physician oversight
Support for long-term health
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Microdosing Compounded Tirzepatide
Promotes metabolic balance
Supports healthy aging
Improves energy & vitality
Physician-guided personalization
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NAD+ Injection
Boosts cellular energy and mitochondrial function
Supports mental clarity and cognitive performance
Aids in recovery and reduces fatigue
Promotes healthy aging and DNA repair
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Glutathione Injection
Powerful antioxidant protection
Detoxifies and boosts immunity
Brightens and smooths skin
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Glutathione Patches
Powerful antioxidant protection
Detoxifies and boosts immunity
Brightens and smooths skin
Once-weekly medical grade patch
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Oral Sermorelin
Supports lean muscle and recovery
Enhances fat metabolism and sleep
Simple oral delivery, no needles
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Oral Compounded GLP-1
Highly effective weight management
Curbs appetite and improves blood sugar
Quick sublingual absorption
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Microdosing Oral Compounded Semaglutide
May help calm inflammation and support immune function
Supports cognitive clarity, mood, and energy
Low-dose protocol designed to minimize side effects
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Hair Regrowth Serum
Easy application to regrow hair in 8-16 weeks
Improve hair thickness and density
Easy once-daily topical application
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Hair Regrowth Spray
Helps maintain and regrow existing hair for fuller-looking hair
Backed by decades of use, minoxidil is a trusted ingredient with a strong safety and efficacy record
Designed for safe, consistent, long-term application under provider guidance
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Oral Minoxidil
Supports hair regrowth in both men and women in 3-6 months
Convenient once-daily oral tablet
May work when topical minoxidil hasn't
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NAD+ Nasal Spray
Boosts energy and mental clarity
Supports healthy aging and repair
Simple daily nasal delivery
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NAD+ Face Cream
Rejuvenate skin cells for a youthful appearance
Enhance natural hydration and smoothness
Reduce the appearance of fine lines and wrinkles
Boost skin elasticity for a firmer, tighter feel
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NAD+ Patches
Boosts energy and brain function
Supports cellular repair and focus
Once-weekly medical grade patch
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Wegovy®
FDA-approved GLP-1 treatment
Supports weight and appetite control
Weekly pre-filled injection pens
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Zepbound®
FDA-approved GLP-1 + GIP treatment
Supports weight and appetite control
Weekly pre-filled injection pens
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Mounjaro®
FDA-approved GLP-1 + GIP treatment
Supports weight and appetite control
Weekly pre-filled injection pens
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Ozempic®
FDA-approved GLP-1 treatment
Supports weight and appetite control
Weekly pre-filled injection pens
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Generic Liraglutide
GLP-1 therapy that helps reduce appetite and promote sustainable weight loss
Supports improved blood sugar and metabolic health
Daily dosing with gradual titration for better tolerance
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Rosacea Treatment
Targets redness, breakouts, and rough texture with four active ingredients
Combats common causes of Rosacea and calms inflammation
Strengthens the skin barrier and reduces flare-ups over time
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Anti-Aging Complex
Smooths wrinkles and fine lines
Brightens tone and texture
Prescription-strength nightly cream
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Acne Cream
Clears active acne fast: Combines tretinoin and clindamycin to fight bacteria and unclog pores
Prevents new breakouts: Keeps follicles clear and reduces inflammation over time
Fades marks and smooths skin: Helps lighten post-acne hyperpigmentation and improve skin texture
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Oral Acne Treatment
Effective treatment for hormonal acne, especially jawline and cystic breakouts
Reduces oil production and inflammation within weeks
Ideal when topical treatments alone aren't enough
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The Spot Corrector
Fades dark spots and discoloration: Targets melanin production and inflammation to visibly even skin tone
Hydroquinone-free and skin-safe: Suitable for long-term use and all skin types
Restores and protects: Niacinamide helps repair the skin barrier, reducing sensitivity and redness
Works well under makeup or layered with moisturizer
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Metformin
Balances blood sugar and insulin use
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Trusted by doctors for 60+ years
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